Researchers still do not have a comprehensive picture of the factors that influence gene expression in human cancers. Understanding gene expression in cancer is important because it can reveal how the ...

Twenty years ago last month, scientists sequenced the first human genome in the landmark Human Genome Project. Among the many things they discovered was that while any two humans have 99.6 percent of ...

Researchers have significantly expanded the catalogue of known human genetic variation. The resulting datasets, shared in two back-to-back publications in the journal Nature, constitute what may be ...

The present theory offers a unified solution to three closely related evolutionary problems. (1) Why does an evolving population explore only a small fraction of the accessible pathways in genotype ...

Humans are still evolving, and Tatum Simonson, PhD, founder and co-director of the Center for Physiological Genomics of Low Oxygen at University of California School of Medicine, plans to use ...

There are a number of C. trachomatis gene products that exhibit variability and may modulate disease severity (Figure 3). The major categories of variable chlamydial gene products and their roles in ...

In a recent study in PNAS, a team of researchers at the Max Planck Institute for Chemical Ecology in Jena, Germany, shows that a single mutation that has immediate effects on plant fitness is ...